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Index
AI Drug Discovery Index
official“An index of biopharma and biotech companies using AI/ML to compress drug discovery timelines — generative chemistry, lab automation, and biology foundation models.” — by Sam Klein
built · 2026-04-30 21:38·rebalance · semiannual·next run · 2026-10-30
backtest · S&P 500 (SPX)·range
CAGR—
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Sharpe—
Sortino—
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Best year—
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risk-free raterf = 4.50%
vs S&P 500 (SPX) · 1M—
vs S&P 500 (SPX) · 1Y—
vs S&P 500 (SPX) · 2Y—
vs S&P 500 (SPX) · 3Y—
vs S&P 500 (SPX) · 5Y—
vs S&P 500 (SPX) · 10Y—
no backtest data
sharpe ratio
| ticker | weight | YTD | 1Y | 3Y | 5Y | 10Y |
|---|---|---|---|---|---|---|
| RXRX | 10.0% | — | — | — | — | — |
| SDGR | 10.0% | — | — | — | — | — |
| ABSI | 10.0% | — | — | — | — | — |
| CRSP | 10.0% | — | — | — | — | — |
| GH | 10.0% | — | — | — | — | — |
| ILMN | 10.0% | — | — | — | — | — |
| TEM | 10.0% | — | — | — | — | — |
| VEEV | 10.0% | — | — | — | — | — |
| CRL | 10.0% | — | — | — | — | — |
| MRK | 10.0% | — | — | — | — | — |
| weighted | 100% | — | — | — | — | — |
attribution factsheet
holdings · 10
click a row to drill in ↗NameAllocationRationale
RXRXRecursion PharmaceuticalsHealthcare10.00%AI-driven phenomics platform with NVIDIA partnership.SDGRSchrödingerHealthcare10.00%Computational chemistry platform powering Big Pharma collaborations.ABSIAbsciHealthcare10.00%Generative-AI antibody design with multiple Big Pharma deals.CRSPCRISPR TherapeuticsHealthcare10.00%Casgevy launch and AI-guided gene-edit pipeline.GHGuardant HealthHealthcare10.00%Liquid biopsy data feeding precision oncology AI models.ILMNIlluminaHealthcare10.00%Sequencing data foundation for biology AI models.TEMTempus AIHealthcare10.00%Multi-modal oncology AI with leading clinical data network.VEEVVeeva SystemsHealthcare10.00%Clinical trial software backbone of pharma R&D.CRLCharles River LaboratoriesHealthcare10.00%Preclinical CRO embedding AI into discovery workflows.MRKMerckHealthcare10.00%Multiple AI partnerships across discovery and protein design.
weighting · equal
rebalance · semiannual